Cocooned Health

Episode 4: A vaccine given to mum but for bub - Whooping Cough: The Pertussis Prevention Prescription. Expert Guest: Professor Adam FinnDr Lydia Yarlott & co-host Dr Eliz Kilich, is joined by our special guest  Professor Adam Finn,
who is a Professor of Paediatrics at the University of Bristol, in the UK.
His research interests include immunity to bacterial respiratory illnesses. He is also a senior clinician in the paediatric immunology and infectious diseases service at Bristol Royal Hospital for Children and the South West region and heads the Bristol Vaccine Centre. 
In addition, he was Chairman of the WHO European Technical Advisory Group of Experts on Immunization from 2011 to 2022. He has spent ten years as ex officio member of the WHO Strategic Advisory Group of Experts, Member of the UK Department of Health Joint Committee on Vaccination and Immunisation from 2014-2024). He also spent 4 years during 2015-2019 as President of the European Society for Paediatric Infectious Diseases.Also check out Professor Adam Finn's TED talk below:Tinyurl.com/afinnwhoop
References: 
Amirthalingam, Gayatri et al. “Effectiveness of maternal pertussis vaccination in England: an observational study.” Lancet (London, England) vol. 384,9953 (2014): 1521-8. doi:10.1016/S0140-6736(14)60686-3
D'Heilly C, Switzer C, Macina D. Safety of Maternal Immunization Against Pertussis: A Systematic Review. Infect Dis Ther. 2019 Dec;8(4):543-568. doi: 10.1007/s40121-019-00265-6. Epub 2019 Sep 17. PMID: 31531826; PMCID: PMC6856234.Briga, M., Goult, E., Brett, T.S. et al. Maternal pertussis immunization and the blunting of routine vaccine effectiveness: a meta-analysis and modeling study. Nat Commun 15, 921 (2024). https://doi.org/10.1038/s41467-024-44943-7Abu-Raya B, Forsyth K, Halperin SA, Maertens K, Jones CE, Heininger U, Hozbor D, Wirsing von König CH, Chitkara AJ, Muloiwa R, Tan TQ. Vaccination in Pregnancy against Pertussis: A Consensus Statement on Behalf of the Global Pertussis Initiative. Vaccines (Basel). 2022 Nov 23;10(12):1990. doi: 10.3390/vaccines10121990. PMID: 36560400; PMCID: PMC9786323.
Aim of the Podcast
What is Whooping cough / the bug that causes it - Bordetella pertussis?
Why is the pertussis vaccination and what are the recommendations for it in pregnancy and in childhood?
The safety data for the vaccines
Why the whooping cough/ pertussis vaccine is repeated in infancy after maternal vaccination and the benefits of this approach? 
To talk about newer vaccines that are being developed
Disclaimer: Remember we are sharing our opinions and medical knowledge, and not associated with our affiliations. Note that knowledge evolves over time. Note that this is not direct medical advice as we are not your personal doctors however feel free to share any ideas expressed with your own healthcare professional as needed. This episode is unsponsored and received no financial incentive. 

Episode 3:Expectation Check: COVID Vaccine Safety in Pregnancy. Expert Guest: Dr Manish Sadarangani
Have you wanted more details about the safety of the COVID-19 vaccines?
https://canvas-network.ca/covid-study/ McClymont E, Albert AY, Alton GD, et al. Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes. JAMA. 2022;327(20):1983–1991. doi:10.1001/jama.2022.5906
Velez MP, Fell DB, Shellenberger JP, Kwong JC, Ray JG. Miscarriage after SARS-CoV-2 vaccination: A population-based cohort study. BJOG. 2023 Nov 16. doi: 10.1111/1471-0528.17721. Epub ahead of print. PMID: 37973606. 
Jorgensen SCJ, Drover SSM, Fell DB, Austin PC, D'Souza R, Guttmann A, Buchan SA, Wilson SE, Nasreen S, Schwartz KL, Tadrous M, Wilson K, Kwong JC. Newborn and Early Infant Outcomes Following Maternal COVID-19 Vaccination During Pregnancy. JAMA Pediatr. 2023 Dec 1;177(12):1314-1323. doi: 10.1001/jamapediatrics.2023.4499. PMID: 37870875; PMCID: PMC10594175.
Jorgensen SCJ, Hernandez A, Fell DB, Austin PC, D'Souza R, Guttmann A, Brown KA, Buchan SA, Gubbay JB, Nasreen S, Schwartz KL, Tadrous M, Wilson K, Kwong JC; Canadian Immunization Research Network (CIRN) Provincial Collaborative Network (PCN) Investigators. Maternal mRNA covid-19 vaccination during pregnancy and delta or omicron infection or hospital admission in infants: test negative design study. BMJ. 2023 Feb 8;380:e074035. doi: 10.1136/bmj-2022-074035. PMID: 36754426; PMCID: PMC9903336.
Matsuo K, Green JM, Herrman SA, Mandelbaum RS, Ouzounian JG. Severe Maternal Morbidity and Mortality of Pregnant Patients With COVID-19 Infection During the Early Pandemic Period in the US. JAMA Netw Open. 2023;6(4):e237149. doi:10.1001/jamanetworkopen.2023.7149
Villar, et al. Maternal and neonatal morbidity and mortality Among pregnant women With and without COVID-19 infection The INTERCOVID multinational cohort study. JAMA Pediatr. 2021;175: 817–826 
 
Disclaimer:We discuss the available evidence and aim to keep our listeners as informed as possible. Please review our disclaimer and note that this is not personal medical advice, as we are not your doctors. However, we aim to inform to the best of our ability but as always still consult your own healthcare professional going forward. We do not accept liability for personal decisions made on behalf of the podcast. This episode is unsponsored and received no financial incentive. 

We discuss the available evidence and aim to keep our listeners as informed as possible. Please review our disclaimer and note that this is not personal medical advice, as we are not your doctors. However, we aim to inform to the best of our ability but as always still consult your own healthcare professional going forward. We do not accept liability for personal decisions made on behalf of the podcast. Disclaimer: Remember we are sharing our opinions and medical knowledge, and not associated with our affiliations. Note that knowledge evolves over time. Note that this is not direct medical advice as we are not your personal doctors however feel free to share any ideas expressed with your own healthcare professional as needed. This episode is unsponsored and received no financial incentive. 

Welcome to Cocooned, part of CocoonedHealth podcasts. This is your podcast on infections and immune protection for the whole family. Whilst starting as a podcast focusing on the pregnancy and newborn period we have expanded to the whole family. We are: Dr Eliz Kilich 👩‍⚕️ Infectious Diseases ST4, UK & Dr Lydia Yarlott 👩‍⚕️ST4, UK 🎤 NB: This is not direct personal medical advice but we hope to elaborate on the most up to date science backing and understanding recommendations in detail.